Setting. Eye Hospital of Wenzhou Medical College, Wenzhou, China.

Methods. The CCT, ACD endothelium to lens, ACD epithelium to lens, and K (mean; in flattest meridian; in steepest meridian) were measured 5 times using the LenStar/Biograph OLCR biometer and 3 times with the Pentacam Scheimpflug system in eyes of healthy volunteers. Concordance was evaluated using paired t tests, the Pearson correlation, and Bland-Altman analyses.

Results. The CCT, ACD endotheliumto lens, and ACDepitheliumto lensmeasured with the Scheimpflug system were slightly, albeit significantly, higher than with the OLCR biometer (P<.05); the respective 95% limits of agreement (LoA) were -8.2 µm to 15.7 µm, -0.11 to 0.15 mm, and -0.13 to 0.17 mm. However, the Scheimpflug system gave significantly flatter readings for K in the flattest meridian (95% LoA, -0.54 to 0.32 diopters [D]), K in the steepest meridian (95% LoA, -0.63 to 0.45 D), and mean K (95% LoA, -0.53 to 0.33 D) (P<.001). The CCT, ACD, and K readings were all highly correlated between the 2 devices (r >0.95, P<.001).

Conclusions. The CCT and ACD measurements with the OLCR biometer and Scheimpflug system can be used interchangeably in healthy young subjects. However, for K measurements, these devices have wide LoA so may not be interchangeable under certain clinical circumstances.

J Cataract Refract Surg. Vol 37, February 2011
Submitted 30 November 2009; Final revision submitted 27 July 2010.
Accepted 13 August 2010.

Jinhai Huang, MD, Konrad Pesudovs, PhD, Daizong Wen, MD, Shihao Chen, MD, OD, Thomas Wright, BPsyc (Hons), Xiaoyu Wang, MD, Yini Li, MD, Qinmei Wang, MD
From the School of Optometry and Ophthalmology and Eye Hospital, Wenzhou Medical College, and the Key Laboratory of Vision Science (Huang, Wen, Chen, X. Wang, Li, Q. Wang), Ministry of Health P.R. China, Wenzhou, China;
the NH&MRC Centre for Clinical Eye Research (Pesudovs, Wright), Department of Optometry and Vision Science, Flinders Medical Centre, and Flinders University of South Australia, Bedford Park, South Australia, Australia.