Iridoschisis is a rare condition in which a localised area of iris stroma is cleaved in two with the anterior atrophic portion disintegrating into fibrils.  The most common presentation of iridoschisis is as an age-related iris atrophy in association with glaucoma.  The association includes angle-closure glaucoma, angle-recession glaucoma and open-angle glaucoma.  A finding of iridoschisis is a warning to the clinician to assess the patient for pre-existing glaucoma and to monitor for glaucomatous changes as it is unclear if iridoschisis is a cause or an effect of raised intraocular pressure (IOP).

Clin Exp Optom 1999;82:1:29-33